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They also covered:
– The various mechanisms by which uric acid causes cellular dysfunction and insulin resistance, including oxidative stress, inflammation, and even effectively preventing insulin from leaving the bloodstream.
– The evolutionary reasons why uric acid-induced metabolic dysfunction and weight gain would have historically benefited us in terms of poor access to food and water, making it easier for us to gain weight and gain weight. increase blood pressure. And how we now live in an evolutionary-environmental gap where this survival mechanism now harms us in the face of caloric abundance.
– The different dietary and environmental factors that generate uric acid, including fructose, purine-rich foods and umami foods, dehydration, alcohol, etc.
– Optimal uric acid levels.
– How uric acid alters our hunger signals, pushes us to eat and even promotes risky behavior. We've explained how to reverse high uric acid levels to achieve optimal health.
00:00 – Introduction
03:12 – More than just the drop
05:06 – A causal role
07:44 – The leading cause of death
15:24 – Scalable environmental mismatch
16:58 – High Fructose Corn Syrup
22:27 – The dangers of uric acid
23:38 – Uric acid and dementia
30:33 – Too much fructose
41:32 – Erectile dysfunction and cardiovascular risk
01:03:17 – No need to eat sugar
Transcription and show notes: https://www.levelshealth.com/podcasts/116-uric-acid-a-key-cause-of-weight-gain-diabetes-heart-disease-and-dementia-and- simple-steps-to-lower-it-dr-david-perlmutter-dr-casey-means
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